VITAMIN B12 1mg is a dietary supplement containing the most active form of vitamin B12 (as methylcobalamin). Vitamin B12 contributes to the normal functioning of metabolic processes aimed at energy production, the process of cell division, the normal formation of red blood cells, the normal metabolism of homocysteine, the normal psychological function, the normal function of the nervous and immune systems and the reduction of tiredness and fatigue. Liposomal Vitamin B12 Formula presents the highest levels of bioavailability and absorption, because it combines the best and most active form of vitamin B12 (methylcobalamin) with liposomal technology! Liposomal formulation technology brings about greater absorption and bioavailability of active substances and vitamins Liposomes present several advantages in terms of the delivery of vitamins and nutritional supplements: they protect the active substance from oxidation and degradation at acidic pH of the stomach they increase absorption and bioavailability compared to free and other conventional pharmaceutical carriers (i.e. tablets, suspensions and capsules). Liposomes Liposomes belong to the colloidal dispersions of bioactive molecule transport systems which have the ability to transport them, improving their effectiveness. The dimensions of liposomes, depending on their preparation method and the physicochemical characteristics of their structural units, are of the order of nanometers to a few micrometers. Historically, in the early 1960s, there was a tendency to study the biophysical properties of colloidal systems that had a lipid and phospholipid composition, with the aim of understanding the biophysical functions of cells. The biophysicist AD Bangham studied lipid colloidal dispersions, to simulate cell membranes and study their functionality. Liposomes, since they are prepared from structural materials like those of our cells, have advantages related to 'friendliness' towards human tissues. They have the ability to transport lipophilic bioactive molecules that do not dissolve easily in aqueous media and therefore have absorption and bioavailability problems, e.g. vitamins, curcumin, etc., but also water-soluble or amphiphilic molecules, improving their dissolution rate and absorption through the gastrointestinal lumen. Liposomes can also transport bioactive substances and improve their penetration through the barriers of the gastrointestinal tract and are effective 'vehicles' for transporting bioactive molecules. Liposomal technology and especially the innovative technology of supramolecular phospholipid complexes with a lipid bilayer structure can improve the therapeutic efficacy of dietary supplements and are an innovation in this field, giving high added value to the final dosage form. The text was created in collaboration with the Pharmaceutical Nanotechnology Laboratory of the Department of Pharmacy of the National and Kapodistrian University of Athens. Bibliography: (1) K. Demetzos. 'Pharmaceutical Nanotechnology. Basic Principles and Practical Applications', Parisianou Publishing House, 2014 (2) Y. Perrie, T. Rades 'Pharmaceutical Technology-Transportation and Targeted Action of Drugs', Scientific Editing by K. Demetzos, Parisianou Publishing House, 2016. E.O.F. Notification Number: 50525 / 31.05.2017 (The E.O.F. Notification Number does not constitute a marketing authorization from the E.O.F.) WARNINGS: • Do not exceed the recommended daily dose. • Dietary supplements should not be used as a substitute for a balanced diet. • Keep out of reach of young children. • This product is not intended for the prevention, treatment or cure of any human disease. • Consult your doctor if you are pregnant, nursing, taking medication or have a health condition. Barcode: 5200403400802
