GLUTATHIONE 450mg is a dietary supplement containing glutathione, a tripeptide consisting of 3 amino acids: glutamic acid cysteine glycine Liposomal formulation technology results in greater absorption and bioavailability of active substances and vitamins. Liposomes present several advantages in terms of the delivery of vitamins and dietary supplements: they protect the active substance from oxidation and degradation at acidic pH of the stomach they increase absorption and bioavailability compared to free and other conventional pharmaceutical carriers (i.e. tablets, suspensions and capsules). Liposomes Liposomes belong to the colloidal dispersions of bioactive molecule transport systems which have the ability to transport them, improving their effectiveness. The dimensions of liposomes, depending on their preparation method and the physicochemical characteristics of their structural units, are in the order of nanometers to a few micrometers. Historically, in the early 1960s, there was a tendency to study the biophysical properties of colloidal systems that had a lipid and phospholipid composition, with the aim of understanding the biophysical functions of cells. The biophysicist AD Bangham studied lipid colloidal dispersions, to simulate cell membranes and study their functionality. Liposomes, since they are prepared from structural materials like those of our cells, have advantages related to their 'friendliness' towards human tissues. They have the ability to transport lipophilic bioactive molecules that do not dissolve easily in aqueous media and therefore have absorption and bioavailability problems, e.g. vitamins, curcumin, etc., but also water-soluble or amphiphilic molecules, improving their dissolution rate and absorption through the gastrointestinal lumen. Liposomes can also transport bioactive substances and improve their penetration through the barriers of the gastrointestinal tract and are effective 'vehicles' for transporting bioactive molecules. Liposomal technology and especially the innovative technology of supramolecular phospholipid complexes with a lipid bilayer structure can improve the therapeutic efficacy of dietary supplements and are an innovation in this field, giving high added value to the final dosage form. The text was created in collaboration with the Pharmaceutical Nanotechnology Laboratory of the Department of Pharmacy of the National and Kapodistrian University of Athens. Bibliography: (1) K. Demetzos. 'Pharmaceutical Nanotechnology. Basic Principles and Practical Applications', Parisianou Publishing House, 2014 (2) Y. Perrie, T. Rades 'Pharmaceutical Technology-Transportation and Targeted Action of Drugs', Scientific Editing by K. Demetzos, Parisianou Publishing House, 2016. E.O.F. Notification Number: 48978/ 14-6-2016 (The E.O.F. Notification Number does not constitute a marketing authorization from the E.O.F.) WARNINGS: Do not exceed the recommended daily dose. S/D should not be used as a substitute for a balanced diet. Keep out of reach of young children. This product is not intended for the prevention, treatment or cure of human disease. Consult your doctor if you are pregnant, nursing, taking medication or have a health condition. Barcode: 5200403400680
